Medicines and Drugs Used in Parkinson Disease Treatment

By Ricky Hussey

You only have to see a patient of Parkinson's disease once to be able to make an instantaneous diagnosis of this disease in another. The symptoms are distinct. James Parkinson after whom the disease is named, was the first to give a complete account of this disease in 1817: He described it thus:

'Involuntary tremulous motion, with lessened muscular power, in part, not in action, and even when supported; with a propensity to bend the trunk forward and to pass from a walking to running pace, the senses and intellects being uninjured.'

Parkinson's disease, or Parkinsonism, is a chronic malady of the central nervous system, more common amongst the elderly, and characterized by muscle rigidity, rhythmic tremor, akinesia or immobility, loss of associated movements, and postural instability. The presence of these signs impairs the ability of the patient to make proper voluntary movements and to maintain posture through reflexes. The patient presents a characteristic feature of an expressionless or a 'mask-life' face, and has tremors of the hands. It is called 'shaking palsy'.

Causes: The real cause of this disease is not known. It is a disease of old age, but may also occur in middle age, It has a sporadic onset which is very gradual and prolonged. It is not considered a hereditary disease, although in about 6% cases, it has been found to run in families. The disease effects. 1 in 250 persons after the age of 40 years. It is degenerative disease in which the centers of brain which normally maintain stance and movements lose functional nerve cells. Parkinsonism can sometimes be due to a known cause such as a late complication of viral encephalitis, injury to brain or arteriosclerosis but such cases are not common. Certain anti-psychotic drugs like reserpine, chlopromazine, and haloperidol may cause symptoms similar to Parkinson's disease, but not the actual disease

itself.

Although we do not know the cause of this disease, recent biochemical researches suggest that it may be due to a deficiency of a neurohormone (dopamine) and/or abundance of another neurohormone (acetylcholine) in the brain.

Treatment and Drugs

Some drugs facilitate dopaminergic transmission and reduce the symptoms. These are amantadine and l-deprenyl (Selegiline). With this knowledge, it has now become possible to at least control the symptomes by using specific drugs to correct the neurochemical imbalance, if not to provide a complete cure. Besides drug therapy, it is very important for a patient to undertake suitable physical exercises regularly, to avoid permanent stiffness of the joints. The drugs used in the treatment of Parkinson's disease can be divided into those which correct: 1) the deficiency of dopamine; and 2) the effects caused by excessive

acetylcholine.

AdvCare is one of the Canada leading pharmacy website. First established in January 2000, its mission is to become the number one site for prescription drug and drug store searches.

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Home Remedy for Coronary Heart Disease

By Rick Hutch

Coronary Heart Disease Information

When the coronary arteries fail to supply adequate blood to the heart, it tends to cause a condition referred to as coronary heart disease. It is also known as coronary artery disease (CAD) and atherosclerotic heart disease.

Coronary Heart Disease home remedy treatment is quite effective. Following are some Coronary Heart Disease cure home remedies. Read on for home remedy for Coronary Heart Disease:

Grapes are considered valuable in treating coronary heart disease. You can either eat raw grapes or else go in for grape juice.

Consume loads of fresh apples, as they possess heart-stimulating properties.

Take 1 tsp of raw onion juice empty stomach in the morning, as it is very beneficial in controlling the level of blood cholesterol.

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Calcium channel blockers such as verapamil, diltiazem, or nifedipine may be prescribed to reduce the heart’s oxygen demands and to increase coronary blood flow.

Anticoagulants such as heparin or warfarin will be administered to reduce the risk of blood clots in patients with unstable angina.

Vasodilators such as captopril, enalapril, or hydralazine may be prescribed to expand blood vessels, thus reducing blood pressure and facilitating blood flow.

Other more controversial, alternative therapies include garlic, which may be consumed as deodorized pills, and fish oil (omega-3 fatty acid) supplements. Ongoing studies indicate that large amounts of garlic may have a modest cholesterol-lowering effect. Any benefits of fish oil supplements are offset by the increased calorie and fat intake. Thus, experts recommend eating one or two servings of salmon, cod, or other cold-water fish a week rather than taking fish oil pills.

Still other alternative therapies provide no benefit and should be avoided. These include chelation therapy, a technique used to remove heavy metals such as lead from the blood.

Apples have heart-stimulating properties. Apple juice and apple jam can be taken in liberal amounts.

A prolonged immersion bath at room temperature taken at bedtime on alternative days is also beneficial for the heart patients.

Regular exercise is most important for healthy heart. Brisk walking and any aerobic exercise are the best.

Grapes are effective in heart pain and palpitation of the heart and the disease can be rapidly controlled if the patient adopts an exclusive grapes diet for a few days. Grape juice, especially will be valuable when one is actually suffering from a heart attack. Indian gooseberry is considered an effective home remedy for heart disease. It tones up the functions of all the organs of the body, builds up health by destroying the heterogenous elements and renewing lost energy.

Another excellent home remedy for heart disease is garlic. Its regular use can even reverse the damage to arteries and help heal them. This conclusion has been reached by an Indian doctor, Arun Bordia of Tagore Medical College. He tested garlic on a group of 432 heart disease patients, recovering from heart attacks.

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